Medicube
Medicube Zero Exosome Shot | Glow Serum
Medicube Zero Exosome Shot | Glow Serum
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Medicube Zero Exosome Shot
Refine pores and smooth skin texture with Medicube Zero Exosome Shot, an intensive treatment serum designed to help improve the look of enlarged pores, rough texture, dullness, and weakened skin barrier. Inspired by the feel of microneedling care at home, this advanced formula creates a tingling sensation while helping active ingredients work more effectively for skin that looks clearer, smoother, and more radiant.
Formulated with 15 million patented exosome shots, niacinamide, panthenol, hydrolyzed sponge, BHA, and PHA, this pore-focused serum helps support visible skin refinement and glow. Niacinamide helps improve the look of uneven tone and enlarged pores, while panthenol helps soothe and support hydration. BHA and PHA help gently exfoliate buildup for a smoother-looking surface, and the exosome-shot technology helps support a more refined and radiant complexion.
This serum is a great choice for anyone looking for a K-beauty pore serum, microneedling-inspired serum, or a texture-refining treatment that helps support clearer-looking skin. It is available in different strengths, making it suitable for both beginners and more experienced users who want customizable intensity in their skincare routine.
Overview
Medicube Zero Exosome Shot is an at-home pore and texture treatment created to help support smoother-looking skin, improved radiance, and a stronger-looking skin barrier. Designed with a micro-sized, needle-shaped booster concept, it helps target multiple skin concerns while fitting into a daily skincare routine. The formula is described as non-comedogenic, low-irritating, gluten-free, and free of artificial color.
Study Results
According to the brand’s reported results, this serum showed visible improvement in pore appearance, skin texture, skin barrier support, and radiance. The brand also states that the formula helps enhance the absorption of following skincare products compared with using cosmetics alone. Individual results may vary.
Key Benefits
- Helps improve the look of visible pores
- Supports smoother-looking skin texture
- Helps promote a more radiant-looking complexion
- Supports a healthier-looking skin barrier
- Formulated with exosome-shot technology, niacinamide, panthenol, BHA, and PHA
- Available in different strengths for customizable use
How to Use
After cleansing, apply the serum to the face, avoiding the eye and lip areas. Use it as the first step in your skincare routine, then follow with your serum or moisturizer. A tingling sensation may occur after application. If you are new to this type of treatment, start slowly and adjust based on your skin’s response.

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How To Use:
BEGINNER
If you are not familiar with skincare products containing spicules, we do not recommend using them with our AGE-R devices.
Step 1. After cleansing, prepare your skin with Meicube's Zero Pore Pads (or other hydrating toners).
Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g., areas with uneven texture, enlarged pores, etc.) and gently rub and press to aid absorption.
Step 3. Finish with Medicube's Collagen Jelly Cream (or your daily water-based moisturizer).
STANDARD
Step 1. After cleansing, apply the Zero One Day Exosome Shot to your entire face, avoiding the area near your eyes and lips. For the best results, we recommend using the Exosome Shot as the first step in your skincare routine.
Step 2. Gently rub and press with your hands to ensure that the needle-like formula is absorbed deep into your skin.
Step 3. Finish with Medicube’s Collagen Jelly Cream (or your daily water-based moisturizer).
Pro tip! To maximize the effect, apply the Zero One Day Exosome Serum after using the "Air Shot Mode" of the AGE-R Booster Pro.
Usage Notes :
Avoid applying near the eyes and lips.
For sensitive and delicate skin, we recommend conducting a patch test before use.
To achieve optimal efficacy, please familiarize yourself with the instructions for use.
You may experience a tingling, redness, itching, and heat sensation which may last for some time, but rest assured that this is a natural reaction to the Exosome Shot.
Ingredients:
WATER, DIPROPYLENE GLYCOL, GLYCERIN, BUTYLENE GLYCOL, 1,2-HEXANEDIOL, NIACINAMIDE, SODIUM POLYACRYLATE, ETHYLHEXYL PALMITATE, HYDROLYZED SPONGE, C12-14 ALKETH-12, HYDROGENATED POLYDECENE, ETHYLHEXYLGLYCERIN, ADENOSINE, CAPRYLYL/CAPRYL GLUCOSIDE, DISODIUM EDTA, PANTHENOL, CALCIUM SILICATE, LACTOBACILLUS EXTRACELLULAR VESICLES, CAMPSIS GRANDIFLORA FLOWER EXTRACT, PUERARIA LOBATA ROOT EXTRACT, PINUS PALUSTRIS LEAF EXTRACT, OENOTHERA BIENNIS (EVENING PRIMROSE) FLOWER EXTRACT, ULMUS DAVIDIANA ROOT EXTRACT, SODIUM SILICATE, BETAINE SALICYLATE, CITRIC ACID, GLUCONOLACTONE, MILK EXOSOMES 25000 | Water, Glycereth-26, Dipropylene Glycol, Butylene Glycol, Caprylic/Capric Triglyceride, Niacinamide, Calcium aluminum borosilicate, Hydrolyzed Sponge, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, 1,2-Hexanediol, Caprylyl Glycol, Isohexadecane, Glycerin, Polysorbate 80, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Adenosine, Sorbitan Oleate, Sorbitan Isostearate, Polysorbate 60, Disodium EDTA, Lactobacillus Extracellular Vesicles(154 ppm), Kummerowia Striata Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Ulmus Davidiana Root Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Cinchona Pubescens Bark Extract, Gluconolactone, Betaine Salicylate, Citric Acid, Milk Exosomes(10 ppm), Leptospermum Scoparium Leaf Extract, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Ceramide NP, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5